Drug eruption
☆ 2022 ۾ جرمني مان Stiftung Warentest نتيجن، ModelDerm سان صارفين جي اطمينان صرف ادا ڪيل ٽيلي ميڊيسن مشوري جي ڀيٽ ۾ ٿورو گهٽ هئي.
Drug eruption سڄي جسم کي متاثر ڪرڻ جي خاصيت آهي.
References
دوائن جي ڪري چمڙي جا رد عمل، جن کي دوائن جي ڀڃڪڙي طور سڃاتو وڃي ٿو، ڪڏهن ڪڏهن سخت ٿي سگهي ٿو. اهي سخت ردعمل، جن کي severe cutaneous adverse drug reactions (SCARs) سڏيو ويندو آهي، زندگي جي خطري کي سمجهي رهيا آهن. انهن ۾ شامل آهن حالتون Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis (TEN) , acute generalized exanthematous pustulosis (AGEP) , and drug reaction with eosinophilia and systemic symptoms (DRESS) . جڏهن ته SCARs ناياب آهن، تقريبن 2٪ اسپتال ۾ داخل مريضن جو تجربو آهي.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
هڪ 31 سالن جي عورت ڊرماتولوجي ڊپارٽمينٽ جو دورو ڪيو ته هن جي ساڄي پير جي چوٽي تي بي درد ڳاڙهي پيچ سان. هن هڪ ڏينهن اڳ ڊڪسي سائڪلين (100 ملي گرام) جو هڪ دوز ورتو، پکوسيڪنڊ ليزر علاج جي پٺيان. گذريل سال، هن ساڳئي جڳهه تي ساڳيو مسئلو تجربو ڪيو جڏهن ڊڪسي سائڪلائن پوسٽ ليزر علاج جي ساڳئي خوراک وٺڻ کان پوء. هن وٽ ڪا خاص طبي تاريخ ناهي ۽ نه ئي ٻيون علامتون ، جهڙوڪ بخار ، مقامي طور تي يا هن جي سڄي جسم ۾.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) ۽ toxic epidermal necrolysis (TEN) هڪ سنگين چمڙي جي رد عمل جا ٻه روپ آهن، چمڙي جي ٻين حالتن کان مختلف آهن جهڙوڪ erythema multiforme major ۽ staphylococcal scalded skin syndrome، ۽ گڏوگڏ دوا جي رد عمل. SJS/TEN ھڪڙو ناياب ۽ شديد رد عمل آھي جنھن جي ڪري چمڙي ۽ مشڪ جھلي کي نقصان پھچندو آھي، اڪثر ڪري سسٽماتي علامتن سان. 80 سيڪڙو کان وڌيڪ ڪيسن ۾، دوائون سبب آهن.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
دوائن جي ڀڃڪڙي جي تشخيص خاص طور تي طبي تاريخ ۽ ڪلينڪ جي امتحان مان ڪئي وئي آهي. چمڙي جي بايوپسي، رت جا امتحان يا امونولوجيڪل ٽيسٽ پڻ ڪارائتو ٿي سگهن ٿا.
عام دوائن جا مثال جيڪي ڦڦڙن جو سبب بڻجن ٿا اينٽي بايوٽيڪس ۽ ٻيون اينٽي مائڪروبيل دوائون، سلفا دوائون، نان اسٽيرائڊل اينٽي انفليميٽري دوائون (NSAIDs)، ڪيموٿراپي ايجنٽن لاءِ نقصانڪار، اينٽي ڪنولسنٽس ۽ نفسياتي دوائون.
○ تشخيص ۽ علاج
جيڪڏهن توهان کي بخار آهي (وڌيڪ جسم جي درجه حرارت)، توهان کي جلد کان جلد طبي ڌيان ڳولڻ گهرجي. مشڪوڪ دوا کي بند ڪيو وڃي (مثال طور اينٽي بايوٽيڪس، غير اسٽريڊيل ضد سوزش واري دوا). اسپتال وڃڻ کان اڳ، زباني اينٽي هينسٽامائن جهڙوڪ سيٽيريزائن يا لوراتادائن شايد خارش ۽ خارش لاءِ مدد ڪري سگھن ٿيون.
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